Intraosseous injections with Platelet-Rich Plasma in the Knee or Hip

Are you suffering from osteoarthritis and looking for a solution to avoid surgery?

Intraosseous injections with Platelet-Rich Plasma offer a non-invasive option that can significantly reduce pain and improve mobility.

By stimulating the natural healing processes within the joint, these injections help to restore function, allowing you to enjoy your daily activities without the need for a surgical procedure.

Take control of your health today and discover a treatment that can help you maintain an active lifestyle.

 

intraosseous infiltrations

Specialists in Intraosseous PRP injections in Valencia

I am Miguel Alfonso Porcar, a recognised specialist in traumatology and orthopaedic surgery.

At Regenerat Clinic, we are leaders in the treatment of degenerative conditions such as osteoarthritis of the knee, shoulder, or hip, using bioregenerative therapies with platelet-rich plasma (also known as platelet growth factor treatment) to address various knee, shoulder, or hip conditions.

Intraosseous infiltration with PRP is an innovative biological therapy that promotes cartilage regeneration.

We use intraosseous injections of platelet-rich plasma (PRP) to help our patients return to their optimal level of health and function, often avoiding the need for minimally invasive arthroscopic surgery or the placement of a knee or hip prosthesis.

We also employ the same orthobiological techniques to accelerate recovery, minimise complications, and increase the success rate of certain trauma surgeries.

Intraosseous PRP injections in hip, knee and shoulder

When knee osteoarthritis is severe, Ahlbäck grades 3 and 4, the subchondral bone causes pain and limits function.

Small cracks or microfractures develop and are easily seen on MRI which illuminates as edema.

Bone edema and bone necrosis indicate that osteoarthritis is actively progressing, and patients are much more likely to require a total knee or hip replacement if we do not actively intervene.

In these cases, the intraosseous injection of PRP obtained by extracting the patient’s own blood is the treatment of choice.

In certain procedures, the use of intraosseous growth factors is performed simultaneously with rehabilitative therapy or minimally invasive arthroscopy, since both procedures can be performed together and this enhances their efficacy.

This also applies in the adjunctive treatment of osteochondral lesions to promote fibrocartilage regeneration.

Knee and hip osteoarthritis: intraosseous and intra-articular injections

The paradigms of understanding osteoarthritis have changed in recent years. They are currently focused on three aspects:

  • Osteoarthritis is an inflammatory disease.
  • The joint is an organ where articular cartilage, synovial membrane, synovial fluid and subchondral bone are connected.
  • The subchondral bone is where the whole process of cartilage degeneration begins, so its surveillance is key in early stages in order to prevent and slow down osteoarthrosis.

It has been proven that, in patients with Tonis grade III and Ahlbäck grade III-Iv osteoarthritis, the combination of intraosseous infiltrations of Platelet Rich Plasma (PRP) has improved pain and functionality of the affected hip or knee, delaying the need for arthroplasty.

References

Intraosseous Infiltration of Platelet-Rich Plasma for Severe Hip OsteoarthritisNicolás Fiz, M.D., Juan Carlos Pérez, M.D., Jorge Guadilla, M.D., Ane Garate, Ph.D.,Pello Sánchez, M.Sc., Sabino Padilla, M.D., Ph.D., Diego Delgado, Ph.D., andMikel Sánchez, M.D.

Intraosseous PRP treatment: effect of the intraosseous injection in Hip or Knee

  • Anti-inflammatory effect: it blocks the production of inflammatory cytokines, while favoring the synthesis of anti-inflammatory cytokines.
  • Analgesic effect or pain reduction: it produces an endogenous response that in inflammatory conditions reduces pain.
  • Regenerative effect: accelerates the healing of injured tissues (tendons, cartilage, muscles, bones, etc.), stimulating the production of stem cells in the area of injury, replacing damaged cells and stimulating the production of extracellular matrix, increasing joint and muscle mobility and functionality and reducing recovery time and time off work in pathologies such as bone edema.

 

Intraosseous Injections: Frequently Asked Questions

Do intraosseous injections hurt?

Most of the time, intraosseous (IO) injections are performed under sedation in an outpatient surgical centre, which helps to minimise pain.

What type of patients are candidates for intraosseous infiltration?

Candidates for intraosseous infiltration include patients with severe osteoarthritis, with or without bone marrow edema lesions, trabecular fractures, inflammatory bone pathology, and localized pain corresponding to their MRI findings.

Generally, these patients have not achieved the expected results with conservative treatments and wish to avoid joint replacement surgery or are not ideal candidates due to factors such as age, activity level, weight, or underlying medical conditions.

What do intraosseous infiltrations consist of?

The technique consists of a subchondral infiltration of Platelet-Rich Plasma (PRP) with growth factors into the acetabulum (5 cc) and the subchondral bone of the femoral head (5 cc) in the case of the hip.

For osteoarthritis of the knee, infiltration is performed on the subchondral surfaces of the tibial plateau and femoral condyle.

We then perform another ultrasound-guided infiltration of intra-articular PRP at 15 days and 30 days.

This technique has a powerful regenerative effect because it neutralises all inflammatory cytokines (IL-1β, TNF-α, etc.).

Intraosseous infiltrations of Platelet Rich Plasma

Opinions on Intra-articular and Intraosseous Injections

El Doctor Miguel Porcar me ha tratado muy bien . Vine con problema de espalda y cadera, está todo solucionado. La atención ha sido excelente. Lo recomiendo a todos.
Mari carmen Fos Avatar
Mari carmen Fos
3/12/2024
Fui con mucho dolor en las rodillas , el doctor Miguel Alfonso Porcar me recomendó Ácido hialurónico , trato muy personal y agradable por parte de todo el equipo .
Roberto Lima Avatar
Roberto Lima
3/02/2024
Inmejorable mi experiencia en Regenerat. En todo momento el trato y la atención con que me atendieron fue muy amable y profesional. Todo fue como el doctor me explicó. Al principio dudé del tratamiento debido a que ya había recibido una infiltración para mi fascitis plantar sin notar mejoría y padeciendo un dolor insoportable. Pero en esta ocasión, el doctor Alfonso me durmió el pie para que la infiltración fuese totalmente indolora. También es de agradecer que todo esto fuese en mi primera consulta y que en la misma, sin necesidad de volver en otra ocasión, tuve la confirmación de mi diagnóstico y se me plantearon todas las opciones posibles para tratarlo, de entre las cuales escogí el tratamiento con prp de mi propia sangre. La primera semana tuve alguna molestia, pero fue controlada con la medicación pautada por el doctor. Tal y como me comentó el doctor, los efectos positivos los empecé a notar tras el primer mes de la infiltración. Ahora, tras dos meses y medio desde la infiltración, puedo decir que me he olvidado ya de mi fascitis. Muchas gracias al doctor Alfonso y a su equipo.
Adriana Vicente Avatar
Adriana Vicente
4/20/2024

Elite athletes and sports professionals trust the specialists at Regenerat Clinic for their recovery! Join them.

New opening Regenerat: Orthopaedic surgeon in Gandía, Denia, Jávea….

Specialists in Regenerative Medicine and Physiotherapy in Gandía

Call ☎ 961 146 834

Regenerat is a paediatric and adult trauma clinic, specialising in regenerative medicine treatments that delay and, in many cases, avoid orthopaedic surgery.

Our patients get an unbiased diagnosis and we offer you various surgical and non-surgical treatment options.

The most common pathologies treated at our medical center are osteoarthritis, back pain, tendon injuries, and sports injuries.

 

Serving patients from Denia to Javea and throughout Alicante: Expert care at our Gandia clinic.

We are located at C/ Ciutat de Laval, 23, 46702 Gandia, Valencia, Spain.

Make an appointment in Gandia, Catarroja or Torrent

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Regenerat clinic: III Wellness and Quality of Life Awards

Reference Center in Regenerative Therapies

The headquarters of the newspaper La Razón in Madrid hosted the gala ceremony of the third edition of the Wellness and Quality of Life Awards,

These awards recognize the work of companies and professionals who help to improve people’s lives.

The effort to change or improve aspects of our society is a task that requires dedication, creativity and innovation on the part of professionals and companies.

Today we celebrate the 3rd edition of the #WellnessQualityAwardsLR to reward and recognize them for it.

Regenerat clinica receives the “Center of reference in regenerative therapies” award.

 

Contact information

☎ 961 146 834

info@regeneratclinica.com

Schedule

Mornings – 9:30am – 14:00pm
Afternoons – 16:00pm – 20:00pm
Saturday & Sunday – Closed

Regenerat Clinic in Catarroja

Carrer Emili Ferrer Gómez, 4, 46470

Regenerat Clinic in Torrent

C/ del Mestre Lorenzo Fuertes Julvez, 14, 46901

Regenerat Clinic in Gandia

C/ Ciutat de Laval, 23, 46702 Gandia, Valencia