Monocyte Therapy for Knee, Shoulder, or Hip Osteoarthritis
Blood monocyte therapy: Eliminate your pain and improve your mobility quickly and permanently
For the first time, with monocyte treatment, we not only treat pain, we help your joint repair itself from within, safely, in a personalized way, and with results that will mark a before and after in your mobility.
Blood monocyte therapy for the treatment of knee osteoarthritis represents the most promising advance in regenerative medicine in traumatology. It is a biological, non-surgical alternative that uses your body’s innate power to heal itself.
Specialists in blood monocyte therapy for the treatment of osteoarthritis of the knee, shoulder, hip, etc. in Valencia.
I am Miguel Alfonso Porcar , a renowned orthopedic surgeon specialized in regenerative medicine and orthopedic surgery.
Pioneers in monocyte therapy in Valencia
At our clinic, we are leaders in advanced biological treatments for joint regeneration. Monocyte therapy is part of our comprehensive approach to regenerative medicine and traumatology, offering our patients an effective, non-surgical alternative for osteoarthritis and other joint injuries.
Our medical team is made up of specialists in traumatology and regenerative medicine with extensive experience in cell therapies. Each treatment is personalised, using validated clinical protocols and state-of-the-art technology to ensure maximum safety and efficacy.
Thanks to our experience, many patients who had lost hope of avoiding surgery have regained mobility, reduced pain, and improved their quality of life.
We are leaders in joint regeneration. And we do it with the most advanced technology available: your own body as medicine.
Monocyte Cell Concentrate (MCC): A biological, non-surgical solution for osteoarthritis and joint injuries
When the body stops regenerating, it is not just a matter of collagen deficiency or ageing: it is an immune imbalance.
MONOCYTES is a new generation of regenerative medicine that uses your own immune system to repair what chronic inflammation had blocked. It works directly on the source, reprogramming inflammation to restore your tissues’ ability to repair themselves.
At REGENERAT, we believe that regeneration is not about promising miracles, but rather reactivating the body’s natural biology with rigour, precision and humanity.
What are monocytes?
Monocytes are immune system cells that play an essential role in tissue repair. When an injury or damage occurs due to osteoarthritis, monocytes rush to the affected area to release cytokines and growth factors, proteins that activate the body’s natural cell regeneration mechanisms.
Las infiltraciones con concentrado celular de monocitos (CCM) representan uno de los mayores avances en medicina regenerativa aplicada a la traumatología.
The CCM concentrates these cells with high repair potential, eliminating pro-inflammatory cells and retaining only those with regenerative capacity.
It is a biological and autologous treatment—meaning it is obtained from your own blood—that naturally stimulates the repair and regeneration processes of joint tissue.
The entire process is carried out in a closed and secure system, ensuring maximum sterility and precision during collection and infiltration.
Monocyte infiltrations: accuracy and safety
The concentrate is injected directly into the affected joint—knee, hip, shoulder, or other damaged areas—using real-time ultrasound guidance, which allows for complete precision when treating the injured tissue.
Why choose monocyte therapy?
Unlike conventional treatments that only relieve pain, CCM works on the root cause of the problem, stimulating cartilage regeneration and slowing the progression of osteoarthritis.
This treatment is recommended for those who wish to avoid surgery and regain their mobility in a lasting way.
What are the benefits of monocyte treatment for osteoarthritis?
- Slows the progression of osteoarthritis in the knee, hip, shoulder, or other joints.
- Accelerates tissue healing.
- Reduces inflammation and pain.
- Improves joint function and mobility.
- Promotes biological regeneration of cartilage.
Overall improvement in quality of life: By reducing pain and restoring joint function, patients regain their mobility and can once again enjoy a more active life, free from limitations.
Safe alternative to anti-inflammatory drugs: Ideal for those who cannot tolerate or prefer to avoid long-term medication, monocyte treatment offers an effective, natural option free from the side effects associated with traditional drugs.
Biological basis: why monocyte therapy?
Monocytes are one of the most versatile cells in the immune system. They are responsible for recognizing damage, cleaning injured tissues, and activating regeneration.
When they reach inflamed tissue, they can transform into macrophages, and their behavior will determine whether the injury worsens or resolves.
- M1 macrophages are pro-inflammatory: they eliminate pathogens, but if they remain active for too long, they perpetuate destruction and pain.
- Los macrófagos M2 son pro-resolutivos: reducen la inflamación, estimulan la producción de colágeno, promueven la angiogénesis y coordinan la reparación.
The concentrate obtained with MONOCYTES promotes polarization towards the M2 profile, inducing an anti-inflammatory, analgesic, and reparative microenvironment.
Key regenerative mechanisms of monocytes
1. Immunomodulation of synovitis
In osteoarthritis or chronic synovitis, macrophages in the synovial fluid are responsible for pain and cartilage degradation. MONOCYTES helps reduce the release of IL-1 and TNF-α, and increases IL-1Ra, a powerful natural anti-inflammatory antagonist.
2. Regeneration of cartilage and subchondral bone
Macrophages activate signals such as BMP-2 and IGF-1, which stimulate chondrocytes and osteoblasts. This promotes collagen formation and bone remodeling in damaged areas.
3. Muscle repair
After muscle injury, monocytes are the main source of IGF-1, a molecule that activates the satellite cells responsible for regenerating fibers.
4. Restoration of joint lubrication
Macrophages balance the production of hyaluronic acid and lubricin, which are essential for maintaining the rheology of synovial fluid and reducing intra-articular friction.
5. Neuromodulatory effect
By resolving local inflammation, peripheral nerve sensitivity is reduced, improving pain even in chronic phases.
Benefits of monocyte therapy
✅ Reduction in pain and progressive improvement in joint mobility.
✅ Reduction of synovitis and control of local inflammation.
✅ Acceleration of cartilage and bone repair processes.
✅ Prolonged immunomodulatory effect, with reduction of pro-inflammatory cytokines.
✅ Less need for additional injections and better tolerance than PRP or corticosteroids.
✅ Personalised, safe and minimally invasive treatment.
Results usually begin to be noticeable between 4 and 8 weeks, with consolidation at 3–6 months, depending on the condition and individual response.
How is monocyte treatment performed?: A safe, quick, outpatient procedure.
We know that safety and comfort are your primary concerns. That is why the Monocyte Cell Concentrate (MCC) procedure is designed to be minimally invasive and highly effective.
Step 1: Extraction and preparation
The process is as simple as a routine blood test.
A small amount of your blood is taken (usually between 60 and 120 ml).
Step 2: Filtration and concentration of monocytes
This blood is immediately processed in MONOCYTES, a closed system, a sterile and safe kit that, without the need for centrifugation (which minimises cellular stress), selects and concentrates the fraction containing the optimal dose of monocytes and regenerative factors.
The entire process takes only between 25 and 40 minutes.
Step 3: Ultrasound-guided infiltration: Maximum precision
The cell concentrate is not injected ‘blindly’. The key to efficacy and safety is ultrasound-guided infiltration.
- The specialist uses a high-resolution ultrasound scanner to visualise the joint and ensure that the monocyte concentrate is applied directly to the exact point of the injury or the area with the most severe cartilage damage.
- The procedure is performed on an outpatient basis in the doctor’s office, under local anaesthesia. It is virtually painless and does not require surgery or hospitalisation.
After the session, the patient can return to their normal life within 24 hours. Relative rest and progressive physiotherapy are recommended from the first week onwards.
Why undergo monocyte therapy for osteoarthritis at Regenerat?
At REGENERAT, treatment is carried out under the same clinical standards and traceability as a hospital medical procedure.
- Batch registration and kit expiry date.
- Documentation in electronic medical records (CliniWIN).
- Procedure checklist signed by the team.
- Structured clinical follow-up (2, 8, 12 weeks, 3 and 6 months).
- Objective scales: VAS, WOMAC, KOOS, OMERACT-OARSI.
¿Por qué hacerlo en REGENERAT?
Because not all cellular treatments are the same, nor do all centres apply the same standards. At REGENERAT, we combine science, technology and clinical ethics to offer real and safe results.
Technology and precision
- Original, certified MONOCYTES system without centrifugation.
- Infiltration 100% eco-guided by medical specialists.
- Standardised and audited procedures across locations.
Multidisciplinary team
- Doctors specialising in regenerative medicine and advanced traumatology.
- Physiotherapists specialising in functional rehabilitation.
- Care coordination and continuous patient monitoring.
REGENERAT philosophy
- “Minimal intervention, maximum functional benefit.”
- Honest communication, shared decisions.
- Regenerative medicine based on evidence, not promises.
Frequently asked questions about monocyte therapy
How many sessions are necessary?
Usually a single infiltration. If the response is partial, it may be repeated after 8–12 weeks.
When will I notice the results of monocyte treatment?
It depends on the condition, but gradual improvement is usually observed between 4 and 8 weeks.
Is it compatible with PRP or shock waves?
Yes. In fact, it can be strategically combined in mixed protocols with PRP or ESWT to enhance results.
What are the side effects of monocyte therapy?
No significant complications have been reported. Mild post-infiltration effects disappear within 1–3 days.
Is this type of treatment approved?
Yes. MONOCYTES is a CE-marked medical device, validated for autologous use in regenerative medicine.
Is it for you?
MONOCYTES can assist you if:
- You suffer from osteoarthritis or persistent synovitis that limits your daily life.
- You are seeking a biological, non-surgical alternative.
- You have tried PRP or hyaluronic acid without success.
- You want to reduce your pain without relying on medication.
What is the price of monocyte treatment for the knee?
The price of each treatment session with monocytes in the knee, shoulder, hip, etc., using ultrasound to inject the monocyte cell concentrate into the exact point of the injury, is €1,400.
In the vast majority of cases, only one session is necessary.
Injuries treated with monocyte therapy in Valencia
Osteoarthritis of the knee, hip and shoulder
Regain mobility and reduce pain without surgery with monocyte therapy
Osteoarthritis causes stiffness, pain and progressive loss of movement. But today, thanks to Monocyte Cell Concentrate (MCC) therapy, it is possible to treat the cause of joint deterioration, not just relieve the symptoms.
This treatment uses your own blood cells with regenerative capacity to reduce inflammation, repair damaged cartilage, and improve joint function.
Ultrasound-guided injections are applied directly to the affected knee, hip or shoulder, stimulating the body’s natural repair mechanisms.
The result: less pain, greater mobility and a real improvement in your quality of life, without resorting to surgery or ongoing drug treatments.
Bone oedema in the knee or hip
Reduce pain and promote bone regeneration with your own biological power.
Bone oedema is an internal bone injury that causes intense and debilitating pain. Instead of prolonged treatments with anti-inflammatories or rest, which do not address the root cause, Monocyte Cell Concentrate (MCC) offers a regenerative approach.
Monocytes release growth factors and cytokines that activate cell repair, improve vascularisation and reduce bone inflammation from within.
As it is an autologous treatment (using your own blood), it is safe, biological and compatible with the body.
Following ultrasound-guided injections, many patients experience a gradual reduction in pain and recovery of function within a few weeks, thus avoiding more aggressive interventions.
Chondromalacia patella
Repair damaged cartilage and restore stability to your knee
Patellar chondromalacia is caused by wear and tear or softening of the cartilage under the kneecap, causing pain when climbing stairs, running or even walking.
Monocyte Cell Concentrate (MCC) acts directly on damaged tissue, stimulating cartilage regeneration and reducing inflammation that aggravates pain.
Thanks to its powerful biostimulating effect, CCM reactivates natural repair processes, improving mobility and strengthening the knee without the need for surgery.
Tendinopathies with poor response to PRP or hyaluronic acid
When PRP or hyaluronic acid are not sufficient, monocytes can make a difference.
In cases of chronic tendinopathies (shoulder, elbow, knee, ankle) that do not improve with PRP or hyaluronic acid, Monocyte Cell Concentrate (MCC) offers a more profound and regenerative alternative.
Monocytes are immune cells capable of modulating inflammation, stimulating tendon fibre regeneration and activating tissue repair in areas where the tissue has lost its ability to recover.
Using ultrasound-guided injections, the concentrate is applied directly to the injured tendon, accelerating regeneration and reducing persistent inflammation.
With CCM, many patients are able to return to movement without pain and without resorting to surgical interventions, regaining strength, flexibility, and confidence in their bodies.
Monocyte therapy reviews
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Price of monocyte treatment for osteoarthritis of the knee, hip, shoulder, tendinopathies, etc.
The price of each infiltration session using ultrasound to inject the monocyte cell concentrate at the exact point of the lesion is €1,350.
These infiltrations are performed with the application of cold and local anesthesia to avoid any type of discomfort during the procedure.
The number of procedures to be performed on each patient depends on the extent of the lesion. One session is usually sufficient.
We finance your treatments in a fast and secure way.
If you wish, we offer immediate financing up to 1000 € interest free.
Regenerat: orthopedic surgery clinic with the best specialist in osteoarthritis of the knee in Torrent
Specialist in orthopaedic surgery and traumatology, regenerative medicine centre in Valencia and physiotherapy clinic in Torrent.
Call ☎ 961 146 834
Regenerat is a pediatric and adult trauma clinic, specialized in regenerative medicine treatments that delay and avoid orthopedic surgery in many cases. Our patients get an unbiased diagnosis and we offer various surgical and non-surgical treatment options.
Although we do not have clinics in these locations, we are the best option for those who are looking for traumatologists in Denia or Jávea…., traumatologists in Aldaia or Alaquás… from our clinics in Torrente or Gandía.
In them we are able to offer innovative treatments to eliminate your osteoarthritis pain, tendinitis… and joint pain, and they are only a few minutes away.
Your health is closer than you think!
We are located at C/ Ciutat de Laval, 23, 46702 Gandia, Valencia, Spain.
Also in C/ del Mestre Lorenzo Fuertes Julvez, 14, 46901 Torrent
Make an appointment in Gandia, Catarroja or Torrent
If you prefer, leave us your details and we will contact you as soon as possible.
Regenerat clinic: III Wellness and Quality of Life Awards
Reference Center in Regenerative Therapies
The headquarters of the newspaper La Razón in Madrid hosted the gala ceremony of the third edition of the Wellness and Quality of Life Awards,
These awards recognize the work of companies and professionals who help to improve people’s lives.
The effort to change or improve aspects of our society is a task that requires dedication, creativity and innovation on the part of professionals and companies.
Today we celebrate the 3rd edition of the #WellnessQualityAwardsLR to reward and recognize them for it.
Regenerat clinica receives the “Center of reference in regenerative therapies” award.
Contact information
☎ 961 146 834
info@regeneratclinica.com
Schedule
Mornings – 9:30am – 14:00pm
Afternoons – 16:00pm – 20:00pm
Saturday & Sunday – Closed
Regenerat Clinic in Catarroja
Carrer Emili Ferrer Gómez, 4, 46470
Regenerat Clinic in Torrent
C/ del Mestre Lorenzo Fuertes Julvez, 14, 46901
Regenerat Clinic in Gandia
C/ Ciutat de Laval, 23, 46702 Gandia, Valencia
